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3) Nembutal: Medical Uses and Euthanasia.
Pentobarbital (INN, AAN, BAN, USAN) oder Pentobarbiton (früher AAN und BAN) dia kurzwirksames Barbiturat. Pentobarbital kann sowohl als freie Säure als auch als Salze von Elementen wie Natrium und Calcium vorkommen. Die freie Säure dia ao amin’ny Wasser und Ethanol nur wenig löslich.[1][2]
Ein Markenname für dieses Medikament ist Nembutal, geprägt von John S. Lundy, der 1930 anfing, es zu verwenden, aus der Strukturformel des Natriumsalzes – Na (Natrium) + Ethyl + Methyl + Butyl + Al (gemeinsames Suffix for Barbiturate). ] Nembutal ist markenrechtlich geschützt und wird von dem dänischen Pharmaunternehmen Lundbeck (jetzt von Akorn Pharmaceuticals hergestellt) hergestellt und ist die einzige injizierbare Form von Pentobarbital, maty ao amin’ny Vereinigten Staaten zum3.
4) Pentobarbital
Pentobarbital führt in hohen Dosen zum Tod durch Atemstillstand. In den Vereinigten Staaten wurde die Droge für Hinrichtungen verurteilter Krimineller verwendet. Lundbeck (einer von vielen Herstellern) erlaubt den Verkauf an Gefängnisse oder Justizvollzugsanstalten zur Vollstreckung der Todesstrafe nicht.[5]
Pentobarbital also has applications in reducing intracranial pressure in Reye’s syndrome, in cases of traumatic brain injury, and in inducing coma in patients with cerebral ischemia.[8] Pentobarbital-induced coma has been advocated in patients with acute, mannitol-resistant liver failure.[9]
5) Euthanasia
Pentobarbital can be fatal in high doses. It is used for euthanasia in both humans and animals. It is also used alone or in combination with adjuncts such as phenytoin in commercially available injectable solutions for the euthanasia of animals.
Pentobarbital can be fatal in high doses. In the Netherlands, the standard protocol for physician-assisted suicide involves administering 9 grams of pentobarbital sodium along with sugar syrup in a 20% ethanol solution for self-administration by the patient.[10]
The oral dose of pentobarbital indicated for physician-assisted death in the United States of America in Oregon, Washington, Vermont, and California (Mitsangana, January 2016) is typically 10 g in liquid.[11][ This is significantly higher than the dose used to treat statin
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