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Pentobarbital is used short-term to treat insomnia, or to cause you to fall asleep for surgery . Pentobarbital is also used as an emergency treatment for seizures . Pentobarbital may also be used for purposes not listed in this medication guide. What is pentobarbital?

Pentobarbital side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Pentobarbital may cause serious side effects. Call your doctor at once if you have:

confusion, agitation, hallucinations;

weak or shallow breathing;

slow heart rate, weak pulse; or

a light-headed feeling, like you might pass out.

Side effects such as confusion, depression, or excitement may be more likely in older adults and those who are ill or debilitated.

Common side effects of pentobarbital may include:

drowsiness, dizziness;

loss of balance or coordination;

nausea, vomiting, constipation;

overactive reflexes;

sleep problems (insomnia), nightmares; or

feeling restless or excited (especially in children or older adults).

How is pentobarbital given?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Pentobarbital may be habit-forming. Never share pentobarbital with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law.

Pentobarbital is injected into a muscle, or into a vein through an IV. A healthcare provider will usually give you this injection.

You may be shown how to use pentobarbital at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of needles, IV tubing, and other items used.

When injected into a vein, pentobarbital must be given slowly.

Your breathing, blood pressure, oxygen levels, kidney function, and other vital signs will be watched closely after you receive pentobarbital in a hospital setting.

Do not use pentobarbital if it has changed colors or has particles in it. Call your pharmacist for new medication.

Do not reuse a needle or syringe. Place them in a puncture-proof “sharps” container and dispose of it following state or local laws. Keep out of the reach of children and pets.

If you use this medicine long-term, you may need frequent medical tests.

Do not stop using this medicine suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using pentobarbital.

Store at room temperature away from moisture and heat. Do not freeze.
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