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Sodium Pentobarbital is a powerful barbiturate used extensively in professional, regulated environments. The primary users include:

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Pre-anesthetic in Lab Settings: Helps in inducing deep sedation for surgical procedures in animal trials.

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Pre-anesthetic in Lab Settings: Helps in inducing deep sedation for surgical procedures in animal trials.

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Nembutal (pentobarbital) belongs to the class of drugs known as barbiturates.

Barbiturates are central nervous system depressant drugs that are often referred to as sedative-hypnotic drugs because, at low doses, they help to initiate sleep (sedative effects), and at higher doses, they can treat issues with anxiety (hypnotic effects).

The major uses of Nembutal are:

For short-term treatment for insomnia (most often used to help people fall asleep but not as useful in helping people stay asleep).
Treatment of anxiety.
As an anticonvulsant in emergency situations.
As a pre-anesthetic for surgery.
The United States Drug Enforcement Administration (DEA) classifies Nembutal as a Schedule II controlled substance, recognizing that the drug has some important medical uses but is also a major candidate for the development of misuse and physical dependence.

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According to the Substance Abuse and Mental Health Services Administration’s (SAMHSA) estimates for 2015, only about 452,000 individuals over the age of 12 in the United States used barbiturate drugs, and an estimated 46,000 of these individuals may have misused a barbiturate at least once.

SAMHSA also reports that barbiturates are most commonly used in hospital settings or clinics. When they are prescribed, barbiturates are more commonly prescribed to elderly people or women.

Nembutal misuse may include:

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Barbiturates are not normally the primary drug of use for individuals who misuse them. Instead, barbiturates and benzodiazepines are more commonly used in conjunction with other drugs.

The most common drug that is used with barbiturates is alcohol, although it is not uncommon for people to mix barbiturates with other barbiturates, benzodiazepines, narcotic pain medications, or nonprescription drugs including cannabis products. Because these drugs are often misused in conjunction with other drugs, the potential to develop very complicated issues with substance use disorders is increased.

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